| Southern Mississippi Schedule: (3-9 / 2-4 as favorite / 1-5 as underdog) ESPN Profile Page |
|---|
| Date |
Away |
Away Score |
|
Home Score |
Home |
Notes |
| 2021-09-04 12:00 Eastern |
Southern Mississippi (-125) |  | 7 |
at |
31 |  | South Alabama (+105) |
Hancock Whitney Stadium, Mobile, AL |
| 2021-09-11 12:00 Eastern |
Grambling | | 0 |
at |
37 | | Southern Mississippi |
M. M. Roberts Stadium, Hattiesburg, MS |
| 2021-09-18 12:00 Eastern |
Troy (-380) |  | 21 |
at |
9 | | Southern Mississippi (+290) |
M. M. Roberts Stadium, Hattiesburg, MS |
| 2021-09-25 12:00 Eastern |
Southern Mississippi | | 14 |
at |
63 |  | #1 Alabama |
Bryant-Denny Stadium, Tuscaloosa, AL |
| 2021-10-02 12:00 Eastern |
Southern Mississippi (+110) | | 19 |
at |
24 |  | Rice (-130) |
Rice Stadium, Houston, TX |
| 2021-10-09 12:00 Eastern |
UTEP (+105) |  | 26 |
at |
13 | | Southern Mississippi (-105) |
M. M. Roberts Stadium, Hattiesburg, MS |
| 2021-10-16 12:00 Eastern |
UAB (-700) |  | 34 |
at |
0 | | Southern Mississippi (+500) |
M. M. Roberts Stadium, Hattiesburg, MS |
| 2021-10-30 12:00 Eastern |
Southern Mississippi (+430) | | 10 |
at |
35 |  | Middle Tennessee (-600) |
Johnny |
| 2021-11-06 12:00 Eastern |
North Texas (-200) |  | 38 |
at |
14 | | Southern Mississippi (+165) |
M. M. Roberts Stadium, Hattiesburg, MS |
| 2021-11-13 12:00 Eastern |
Southern Mississippi | | 17 |
at |
27 |  | #23 UTSA |
Alamodome, San Antonio, TX |
| 2021-11-19 20:00 Eastern |
Southern Mississippi (+550) | | 35 |
at |
19 |  | Louisiana Tech (-800) |
Joe Aillet Stadium, Ruston, LA |
| 2021-11-27 12:00 Eastern |
Florida International (+340) |  | 17 |
at |
37 | | Southern Mississippi (-470) |
M. M. Roberts Stadium, Hattiesburg, MS |
