| Date | Away | | | | | Home | First Pitch | Where |
|---|
| Sep 26 | STL |  | 1 | 12 |  | CHC | Sep 26 02:20 PM EDT (Fri) | Wrigley Field |
| Sep 26 | MIN |  | 1 | 3 |  | PHI | Sep 26 06:45 PM EDT (Fri) | Citizens Bank Park |
| Sep 26 | CHW |  | 10 | 9 |  | WAS | Sep 26 06:45 PM EDT (Fri) | Nationals Park |
| Sep 26 | BAL |  | 4 | 8 |  | NYY | Sep 26 07:05 PM EDT (Fri) | Yankee Stadium |
| Sep 26 | TB |  | 2 | 4 |  | TOR | Sep 26 07:07 PM EDT (Fri) | Rogers Centre |
| Sep 26 | DET |  | 3 | 4 |  | BOS | Sep 26 07:10 PM EDT (Fri) | Fenway Park |
| Sep 26 | TEX |  | 7 | 3 |  | CLE | Sep 26 07:10 PM EDT (Fri) | Progressive Field |
| Sep 26 | NYM |  | 2 | 6 |  | MIA | Sep 26 07:10 PM EDT (Fri) | loanDepot park |
| Sep 26 | PIT |  | 9 | 3 |  | ATL | Sep 26 07:15 PM EDT (Fri) | Truist Park |
| Sep 26 | CIN |  | 3 | 1 |  | MIL | Sep 26 08:10 PM EDT (Fri) | American Family Field |
| Sep 26 | HOU |  | 3 | 4 |  | LAA | Sep 26 09:38 PM EDT (Fri) | Angel Stadium |
| Sep 26 | ARI |  | 4 | 7 |  | SD | Sep 26 09:40 PM EDT (Fri) | Petco Park |
| Sep 26 | LAD |  | 3 | 2 |  | SEA | Sep 26 09:40 PM EDT (Fri) | T-Mobile Park |
| Sep 26 | KC |  | 3 | 4 |  | LV | Sep 26 10:05 PM EDT (Fri) | Sutter Health Park |
| Sep 26 | COL |  | 3 | 6 |  | SF | Sep 26 10:15 PM EDT (Fri) | Oracle Park |
