| Date | Away | | | | | Home | First Pitch | Where |
|---|
| May 22 | TEX |  | 0 | 1 |  | NYY | May 22 12:35 PM EDT (Thu) | Yankee Stadium |
| May 22 | SD |  | 6 | 7 |  | TOR | May 22 01:07 PM EDT (Thu) | Rogers Centre |
| May 22 | PHI |  | 2 | 0 |  | COL | May 22 03:10 PM EDT (Thu) | Coors Field |
| May 22 | LAA |  | 10 | 5 |  | LV | May 22 03:35 PM EDT (Thu) | Sutter Health Park |
| May 22 | CLE |  | 7 | 0 |  | DET | May 22 06:40 PM EDT (Thu) | Comerica Park |
| May 22 | MIL |  | 8 | 5 |  | PIT | May 22 06:40 PM EDT (Thu) | PNC Park |
| May 22 | BAL |  | (postponed) |  | BOS | May 22 06:45 PM EDT (Thu) | Fenway Park (resch May 23) |
| May 22 | ATL |  | 7 | 8 |  | WAS | May 22 06:45 PM EDT (Thu) | Nationals Park |
| May 22 | SEA |  | 2 | 9 |  | HOU | May 22 08:10 PM EDT (Thu) | Daikin Park |
