| Date | Away | | | | | Home | First Pitch | Where |
|---|
| Apr 23 | STL |  | 1 | 4 |  | ATL | Apr 23 12:15 PM EDT (Wed) | Truist Park |
| Apr 23 | SD |  | 0 | 6 |  | DET | Apr 23 01:10 PM EDT (Wed) | Comerica Park |
| Apr 23 | PHI |  | 3 | 4 |  | NYM | Apr 23 01:10 PM EDT (Wed) | Citi Field |
| Apr 23 | CIN |  | 5 | 2 |  | MIA | Apr 23 01:10 PM EDT (Wed) | loanDepot park |
| Apr 23 | NYY |  | 5 | 1 |  | CLE | Apr 23 01:10 PM EDT (Wed) | Progressive Field |
| Apr 23 | BAL |  | 3 | 4 |  | WAS | Apr 23 06:45 PM EDT (Wed) | Nationals Park |
| Apr 23 | SEA |  | 8 | 5 |  | BOS | Apr 23 06:45 PM EDT (Wed) | Fenway Park |
| Apr 23 | LAD |  | 6 | 7 |  | CHC | Apr 23 07:00 PM EDT (Wed) | Wrigley Field |
| Apr 23 | COL |  | (postponed) |  | KC | Apr 23 02:15 PM EDT (Wed) | Kauffman Stadium (resch Apr 24) |
| Apr 23 | TOR |  | 1 | 3 |  | HOU | Apr 23 07:40 PM EDT (Wed) | Daikin Park |
| Apr 23 | CHW |  | 3 | 6 |  | MIN | Apr 23 07:40 PM EDT (Wed) | Target Field |
| Apr 23 | PIT |  | 3 | 0 |  | LAA | Apr 23 09:38 PM EDT (Wed) | Angel Stadium |
| Apr 23 | TB |  | 7 | 6 |  | ARI | Apr 23 09:40 PM EDT (Wed) | Chase Field |
| Apr 23 | MIL |  | 2 | 4 |  | SF | Apr 23 09:45 PM EDT (Wed) | Oracle Park |
| Apr 23 | TEX |  | 2 | 5 |  | LV | Apr 23 10:05 PM EDT (Wed) | Sutter Health Park |
