| Date | Away | | | | | Home | First Pitch | Where |
|---|
| Sep 12 | TB |  | 4 | 6 |  | CHC | Sep 12 02:20 PM EDT (Fri) | Wrigley Field |
| Sep 12 | PIT |  | 5 | 6 |  | WAS | Sep 12 06:45 PM EDT (Fri) | Nationals Park |
| Sep 12 | KC |  | 2 | 8 |  | PHI | Sep 12 06:45 PM EDT (Fri) | Citizens Bank Park |
| Sep 12 | BAL |  | 1 | 6 |  | TOR | Sep 12 07:07 PM EDT (Fri) | Rogers Centre |
| Sep 12 | TEX |  | 8 | 3 |  | NYM | Sep 12 07:10 PM EDT (Fri) | Citi Field |
| Sep 12 | CHW |  | 0 | 4 |  | CLE | Sep 12 07:10 PM EDT (Fri) | Progressive Field |
| Sep 12 | DET |  | 2 | 8 |  | MIA | Sep 12 07:10 PM EDT (Fri) | loanDepot park |
| Sep 12 | NYY |  | 4 | 1 |  | BOS | Sep 12 07:10 PM EDT (Fri) | Fenway Park |
| Sep 12 | HOU |  | 11 | 3 |  | ATL | Sep 12 07:15 PM EDT (Fri) | Truist Park |
| Sep 12 | ARI |  | 8 | 9 |  | MIN | Sep 12 08:10 PM EDT (Fri) | Target Field |
| Sep 12 | STL |  | 2 | 8 |  | MIL | Sep 12 08:10 PM EDT (Fri) | American Family Field |
| Sep 12 | COL |  | 4 | 2 |  | SD | Sep 12 09:40 PM EDT (Fri) | Petco Park |
| Sep 12 | CIN |  | 0 | 3 |  | LV | Sep 12 10:05 PM EDT (Fri) | Sutter Health Park |
| Sep 12 | LAA |  | 1 | 2 |  | SEA | Sep 12 10:10 PM EDT (Fri) | T-Mobile Park |
| Sep 12 | LAD |  | 1 | 5 |  | SF | Sep 12 10:15 PM EDT (Fri) | Oracle Park |
