| Date | Away | | | | | Home | First Pitch | Where |
|---|
| Sep 27 | BAL |  | 1 | 6 |  | NYY | Sep 27 01:05 PM EDT (Sat) | Yankee Stadium |
| Sep 27 | STL |  | 3 | 7 |  | CHC | Sep 27 02:20 PM EDT (Sat) | Wrigley Field |
| Sep 27 | TB |  | 1 | 5 |  | TOR | Sep 27 03:07 PM EDT (Sat) | Rogers Centre |
| Sep 27 | COL |  | 3 | 4 |  | SF | Sep 27 04:05 PM EDT (Sat) | Oracle Park |
| Sep 27 | CHW |  | 5 | 6 |  | WAS | Sep 27 04:05 PM EDT (Sat) | Nationals Park |
| Sep 27 | DET |  | 2 | 1 |  | BOS | Sep 27 04:10 PM EDT (Sat) | Fenway Park |
| Sep 27 | NYM |  | 5 | 0 |  | MIA | Sep 27 04:10 PM EDT (Sat) | loanDepot park |
| Sep 27 | MIN |  | 5 | 0 |  | PHI | Sep 27 06:05 PM EDT (Sat) | Citizens Bank Park |
| Sep 27 | TEX |  | 2 | 3 |  | CLE | Sep 27 07:15 PM EDT (Sat) | Progressive Field |
| Sep 27 | CIN |  | 7 | 4 |  | MIL | Sep 27 07:15 PM EDT (Sat) | American Family Field |
| Sep 27 | PIT |  | 3 | 1 |  | ATL | Sep 27 07:15 PM EDT (Sat) | Truist Park |
| Sep 27 | ARI |  | 1 | 5 |  | SD | Sep 27 08:40 PM EDT (Sat) | Petco Park |
| Sep 27 | HOU |  | 6 | 1 |  | LAA | Sep 27 09:38 PM EDT (Sat) | Angel Stadium |
| Sep 27 | LAD |  | 5 | 3 |  | SEA | Sep 27 09:40 PM EDT (Sat) | T-Mobile Park |
| Sep 27 | KC |  | 4 | 2 |  | LV | Sep 27 10:05 PM EDT (Sat) | Sutter Health Park |
