| Date | Away | | | | | Home | First Pitch | Where |
|---|
| Apr 16 | ATL |  | 1 | 3 |  | TOR | Apr 16 01:07 PM EDT (Wed) | Rogers Centre |
| Apr 16 | NYM |  | 3 | 4 |  | MIN | Apr 16 01:10 PM EDT (Wed) | Target Field |
| Apr 16 | DET |  | 1 | 5 |  | MIL | Apr 16 01:10 PM EDT (Wed) | American Family Field |
| Apr 16 | HOU |  | 1 | 4 |  | STL | Apr 16 01:15 PM EDT (Wed) | Busch Stadium |
| Apr 16 | CHC |  | 2 | 4 |  | SD | Apr 16 04:10 PM EDT (Wed) | Petco Park |
| Apr 16 | CLE |  | 1 | 9 |  | BAL | Apr 16 06:35 PM EDT (Wed) | Oriole Park at Camden Yards |
| Apr 16 | WAS |  | 1 | 6 |  | PIT | Apr 16 06:40 PM EDT (Wed) | PNC Park |
| Apr 16 | SEA |  | 5 | 3 |  | CIN | Apr 16 06:40 PM EDT (Wed) | Great American Ball Park |
| Apr 16 | ARI |  | 6 | 2 |  | MIA | Apr 16 06:40 PM EDT (Wed) | loanDepot park |
| Apr 16 | SF |  | 11 | 4 |  | PHI | Apr 16 06:45 PM EDT (Wed) | Citizens Bank Park |
| Apr 16 | BOS |  | 1 | 0 |  | TB | Apr 16 07:05 PM EDT (Wed) | George M. Steinbrenner Field |
| Apr 16 | KC |  | 3 | 4 |  | NYY | Apr 16 07:05 PM EDT (Wed) | Yankee Stadium |
| Apr 16 | LV |  | 3 | 1 |  | CHW | Apr 16 07:40 PM EDT (Wed) | Rate Field |
| Apr 16 | LAA |  | 1 | 3 |  | TEX | Apr 16 08:05 PM EDT (Wed) | Globe Life Field |
| Apr 16 | COL |  | 7 | 8 |  | LAD | Apr 16 10:10 PM EDT (Wed) | Dodger Stadium |
