| Date | Away | | | | | Home | First Pitch | Where |
|---|
| Apr 18 | ARI |  | 11 | 13 |  | CHC | Apr 18 02:20 PM EDT (Fri) | Wrigley Field |
| Apr 18 | KC |  | 3 | 7 |  | DET | Apr 18 06:40 PM EDT (Fri) | Comerica Park |
| Apr 18 | CLE |  | 10 | 7 |  | PIT | Apr 18 06:40 PM EDT (Fri) | PNC Park |
| Apr 18 | MIA |  | 2 | 7 |  | PHI | Apr 18 06:45 PM EDT (Fri) | Citizens Bank Park |
| Apr 18 | CIN |  | 8 | 3 |  | BAL | Apr 18 07:05 PM EDT (Fri) | Oriole Park at Camden Yards |
| Apr 18 | NYY |  | 1 | 0 |  | TB | Apr 18 07:05 PM EDT (Fri) | George M. Steinbrenner Field |
| Apr 18 | SEA |  | 1 | 3 |  | TOR | Apr 18 07:07 PM EDT (Fri) | Rogers Centre |
| Apr 18 | STL |  | 4 | 5 |  | NYM | Apr 18 07:10 PM EDT (Fri) | Citi Field |
| Apr 18 | CHW |  | 3 | 10 |  | BOS | Apr 18 07:10 PM EDT (Fri) | Fenway Park |
| Apr 18 | MIN |  | 4 | 6 |  | ATL | Apr 18 07:15 PM EDT (Fri) | Truist Park |
| Apr 18 | LAD |  | 3 | 0 |  | TEX | Apr 18 08:05 PM EDT (Fri) | Globe Life Field |
| Apr 18 | SD |  | 4 | 6 |  | HOU | Apr 18 08:10 PM EDT (Fri) | Daikin Park |
| Apr 18 | LV |  | 3 | 5 |  | MIL | Apr 18 08:10 PM EDT (Fri) | American Family Field |
| Apr 18 | WAS |  | (postponed) |  | COL | Apr 18 08:10 PM EDT (Fri) | Coors Field (resch Apr 20) |
| Apr 18 | SF |  | 0 | 2 |  | LAA | Apr 18 09:38 PM EDT (Fri) | Angel Stadium |
