| Date | Away | | | | | Home | First Pitch | Where |
|---|
| Apr 01 | CLE |  | 0 | 7 |  | SD | Apr 01 09:40 PM EDT (Tue) | Petco Park |
| Apr 02 | CLE | | 2 | 5 | | SD | Apr 02 04:10 PM EDT (Wed) | Petco Park |
| Apr 04 | CLE | | 8 | 6 |  | LAA | Apr 04 09:38 PM EDT (Fri) | Angel Stadium |
| Apr 05 | CLE | | 4 | 10 | | LAA | Apr 05 09:38 PM EDT (Sat) | Angel Stadium |
| Apr 06 | CLE | | 2 | 6 | | LAA | Apr 06 04:07 PM EDT (Sun) | Angel Stadium |
| Apr 08 | CHW |  | 0 | 1 | | CLE | Apr 08 04:10 PM EDT (Tue) | Progressive Field |
| Apr 09 | CHW | | 2 | 3 | | CLE | Apr 09 06:10 PM EDT (Wed) | Progressive Field |
| Apr 10 | CHW | | 1 | 6 | | CLE | Apr 10 01:10 PM EDT (Thu) | Progressive Field |
| Apr 11 | KC |  | 0 | 7 | | CLE | Apr 11 06:10 PM EDT (Fri) | Progressive Field |
| Apr 12 | KC | | 3 | 6 | | CLE | Apr 12 06:10 PM EDT (Sat) | Progressive Field |
| Apr 13 | KC | | 4 | 2 | | CLE | Apr 13 01:40 PM EDT (Sun) | Progressive Field |
| Apr 15 | CLE | | 6 | 3 |  | BAL | Apr 15 07:05 PM EDT (Tue) | Oriole Park at Camden Yards |
| Apr 16 | CLE | | 1 | 9 | | BAL | Apr 16 06:35 PM EDT (Wed) | Oriole Park at Camden Yards |
| Apr 17 | CLE | | 2 | 6 | | BAL | Apr 17 06:35 PM EDT (Thu) | Oriole Park at Camden Yards |
| Apr 18 | CLE | | 10 | 7 |  | PIT | Apr 18 06:40 PM EDT (Fri) | PNC Park |
| Apr 19 | CLE | | 3 | 0 | | PIT | Apr 19 04:05 PM EDT (Sat) | PNC Park |
| Apr 20 | CLE | | 5 | 4 | | PIT | Apr 20 01:35 PM EDT (Sun) | PNC Park |
| Apr 21 | NYY |  | 4 | 6 | | CLE | Apr 21 06:10 PM EDT (Mon) | Progressive Field |
| Apr 22 | NYY | | 2 | 3 | | CLE | Apr 22 06:10 PM EDT (Tue) | Progressive Field |
| Apr 23 | NYY | | 5 | 1 | | CLE | Apr 23 01:10 PM EDT (Wed) | Progressive Field |
| Apr 25 | BOS |  | (postponed) | | CLE | Apr 25 01:10 PM EDT (Fri) | Progressive Field (resch Apr 26) |
| Apr 26 | BOS | | 4 | 5 | | CLE | Apr 26 01:10 PM EDT (Sat) | Progressive Field |
| Apr 26 | BOS | | 7 | 3 | | CLE | Apr 26 06:10 PM EDT (Sat) | Progressive Field |
| Apr 27 | BOS | | 13 | 3 | | CLE | Apr 27 01:40 PM EDT (Sun) | Progressive Field |
| Apr 28 | MIN |  | 11 | 1 | | CLE | Apr 28 06:10 PM EDT (Mon) | Progressive Field |
| Apr 29 | MIN | | 1 | 2 | | CLE | Apr 29 06:10 PM EDT (Tue) | Progressive Field |
| Apr 30 | MIN | | 2 | 4 | | CLE | Apr 30 06:10 PM EDT (Wed) | Progressive Field |
