| Date | Away | | | | | Home | First Pitch | Where |
|---|
| May 01 | STL |  | 1 | 9 |  | CIN | May 01 12:40 PM EDT (Thu) | Great American Ball Park |
| May 02 | NYM |  | 9 | 3 | | STL | May 02 08:15 PM EDT (Fri) | Busch Stadium |
| May 03 | NYM | | (postponed) | | STL | May 03 02:15 PM EDT (Sat) | Busch Stadium (resch May 04) |
| May 04 | NYM | | 5 | 6 | | STL | May 04 01:15 PM EDT (Sun) | Busch Stadium |
| May 04 | NYM | | 4 | 5 | | STL | May 04 06:15 PM EDT (Sun) | Busch Stadium |
| May 05 | PIT |  | 3 | 6 | | STL | May 05 07:45 PM EDT (Mon) | Busch Stadium |
| May 06 | PIT | | 1 | 2 | | STL | May 06 07:45 PM EDT (Tue) | Busch Stadium |
| May 07 | PIT | | 0 | 5 | | STL | May 07 01:15 PM EDT (Wed) | Busch Stadium |
| May 09 | STL | | 10 | 0 |  | WAS | May 09 06:45 PM EDT (Fri) | Nationals Park |
| May 10 | STL | | 4 | 2 | | WAS | May 10 04:05 PM EDT (Sat) | Nationals Park |
| May 11 | STL | | 6 | 1 | | WAS | May 11 01:35 PM EDT (Sun) | Nationals Park |
| May 12 | STL | | 3 | 2 |  | PHI | May 12 06:45 PM EDT (Mon) | Citizens Bank Park |
| May 13 | STL | | (postponed) | | PHI | May 13 06:45 PM EDT (Tue) | Citizens Bank Park (resch May 14) |
| May 14 | STL | | 1 | 2 | | PHI | May 14 01:05 PM EDT (Wed) | Citizens Bank Park |
| May 14 | STL | | 14 | 7 | | PHI | May 14 06:15 PM EDT (Wed) | Citizens Bank Park |
| May 16 | STL | | 10 | 3 |  | KC | May 16 07:40 PM EDT (Fri) | Kauffman Stadium |
| May 17 | STL | | 1 | 0 | | KC | May 17 07:10 PM EDT (Sat) | Kauffman Stadium |
| May 18 | STL | | 1 | 2 | | KC | May 18 02:10 PM EDT (Sun) | Kauffman Stadium |
| May 19 | DET |  | 4 | 11 | | STL | May 19 07:45 PM EDT (Mon) | Busch Stadium |
| May 20 | DET | | 5 | 4 | | STL | May 20 07:45 PM EDT (Tue) | Busch Stadium |
| May 21 | DET | | 5 | 1 | | STL | May 21 01:15 PM EDT (Wed) | Busch Stadium |
| May 23 | ARI |  | 3 | 4 | | STL | May 23 08:15 PM EDT (Fri) | Busch Stadium |
| May 24 | ARI | | 5 | 6 | | STL | May 24 02:15 PM EDT (Sat) | Busch Stadium |
| May 25 | ARI | | 3 | 4 | | STL | May 25 02:15 PM EDT (Sun) | Busch Stadium |
| May 26 | STL | | 2 | 5 |  | BAL | May 26 03:05 PM EDT (Mon) | Oriole Park at Camden Yards |
| May 27 | STL | | 7 | 4 | | BAL | May 27 06:35 PM EDT (Tue) | Oriole Park at Camden Yards |
| May 28 | STL | | 6 | 4 | | BAL | May 28 06:35 PM EDT (Wed) | Oriole Park at Camden Yards |
| May 30 | STL | | 1 | 11 |  | TEX | May 30 08:05 PM EDT (Fri) | Globe Life Field |
| May 31 | STL | | 2 | 0 | | TEX | May 31 04:05 PM EDT (Sat) | Globe Life Field |
