| Date | Away | | | | | Home | First Pitch | Where |
|---|
| May 01 | WAS |  | 4 | 2 |  | PHI | May 01 06:45 PM EDT (Thu) | Citizens Bank Park |
| May 02 | WAS | | 1 | 6 |  | CIN | May 02 06:10 PM EDT (Fri) | Great American Ball Park |
| May 03 | WAS | | 11 | 6 | | CIN | May 03 06:40 PM EDT (Sat) | Great American Ball Park |
| May 04 | WAS | | 4 | 1 | | CIN | May 04 04:10 PM EDT (Sun) | Great American Ball Park |
| May 05 | CLE |  | (postponed) | | WAS | May 05 06:45 PM EDT (Mon) | Nationals Park (resch May 06) |
| May 06 | CLE | | 9 | 10 | | WAS | May 06 03:35 PM EDT (Tue) | Nationals Park |
| May 06 | CLE | | 9 | 1 | | WAS | May 06 03:40 PM EDT (Tue) | Nationals Park |
| May 07 | CLE | | 8 | 6 | | WAS | May 07 12:05 PM EDT (Wed) | Nationals Park |
| May 09 | STL |  | 10 | 0 | | WAS | May 09 06:45 PM EDT (Fri) | Nationals Park |
| May 10 | STL | | 4 | 2 | | WAS | May 10 04:05 PM EDT (Sat) | Nationals Park |
| May 11 | STL | | 6 | 1 | | WAS | May 11 01:35 PM EDT (Sun) | Nationals Park |
| May 12 | WAS | | 3 | 4 |  | ATL | May 12 07:15 PM EDT (Mon) | Truist Park |
| May 13 | WAS | | 2 | 5 | | ATL | May 13 07:15 PM EDT (Tue) | Truist Park |
| May 14 | WAS | | 5 | 4 | | ATL | May 14 07:15 PM EDT (Wed) | Truist Park |
| May 15 | WAS | | 2 | 5 | | ATL | May 15 12:15 PM EDT (Thu) | Truist Park |
| May 16 | WAS | | 4 | 3 |  | BAL | May 16 07:05 PM EDT (Fri) | Oriole Park at Camden Yards |
| May 17 | WAS | | 10 | 6 | | BAL | May 17 04:05 PM EDT (Sat) | Oriole Park at Camden Yards |
| May 18 | WAS | | 10 | 4 | | BAL | May 18 01:35 PM EDT (Sun) | Oriole Park at Camden Yards |
| May 20 | ATL | | 3 | 5 | | WAS | May 20 06:45 PM EDT (Tue) | Nationals Park |
| May 21 | ATL | | (postponed) | | WAS | May 21 06:45 PM EDT (Wed) | Nationals Park (resch Sep 16) |
| May 22 | ATL | | 7 | 8 | | WAS | May 22 06:45 PM EDT (Thu) | Nationals Park |
| May 23 | SF |  | 4 | 0 | | WAS | May 23 06:45 PM EDT (Fri) | Nationals Park |
| May 24 | SF | | 0 | 3 | | WAS | May 24 04:05 PM EDT (Sat) | Nationals Park |
| May 25 | SF | | 3 | 2 | | WAS | May 25 01:35 PM EDT (Sun) | Nationals Park |
| May 27 | WAS | | 1 | 9 |  | SEA | May 27 09:40 PM EDT (Tue) | T-Mobile Park |
| May 28 | WAS | | 9 | 0 | | SEA | May 28 09:40 PM EDT (Wed) | T-Mobile Park |
| May 29 | WAS | | 9 | 3 | | SEA | May 29 09:40 PM EDT (Thu) | T-Mobile Park |
| May 30 | WAS | | 9 | 7 |  | ARI | May 30 09:40 PM EDT (Fri) | Chase Field |
| May 31 | WAS | | 11 | 7 | | ARI | May 31 10:10 PM EDT (Sat) | Chase Field |
