| Date | Away | | | | | Home | First Pitch | Where |
|---|
| May 01 | DET |  | 10 | 4 |  | LAA | May 01 09:38 PM EDT (Thu) | Angel Stadium |
| May 02 | DET | | 9 | 1 | | LAA | May 02 09:38 PM EDT (Fri) | Angel Stadium |
| May 03 | DET | | 2 | 5 | | LAA | May 03 09:38 PM EDT (Sat) | Angel Stadium |
| May 04 | DET | | 13 | 1 | | LAA | May 04 04:07 PM EDT (Sun) | Angel Stadium |
| May 06 | DET | | (postponed) |  | COL | May 06 08:40 PM EDT (Tue) | Coors Field (resch May 08) |
| May 07 | DET | | 8 | 6 | | COL | May 07 08:40 PM EDT (Wed) | Coors Field |
| May 08 | DET | | 10 | 2 | | COL | May 08 03:10 PM EDT (Thu) | Coors Field |
| May 08 | DET | | 11 | 1 | | COL | May 08 03:15 PM EDT (Thu) | Coors Field |
| May 09 | TEX |  | 1 | 2 | | DET | May 09 06:40 PM EDT (Fri) | Comerica Park |
| May 10 | TEX | | 10 | 3 | | DET | May 10 06:10 PM EDT (Sat) | Comerica Park |
| May 11 | TEX | | 6 | 1 | | DET | May 11 01:40 PM EDT (Sun) | Comerica Park |
| May 12 | BOS |  | 2 | 14 | | DET | May 12 06:40 PM EDT (Mon) | Comerica Park |
| May 13 | BOS | | 9 | 10 | | DET | May 13 06:40 PM EDT (Tue) | Comerica Park |
| May 14 | BOS | | 5 | 6 | | DET | May 14 06:40 PM EDT (Wed) | Comerica Park |
| May 16 | DET | | 5 | 4 |  | TOR | May 16 07:07 PM EDT (Fri) | Rogers Centre |
| May 17 | DET | | 1 | 2 | | TOR | May 17 03:07 PM EDT (Sat) | Rogers Centre |
| May 18 | DET | | 3 | 2 | | TOR | May 18 01:37 PM EDT (Sun) | Rogers Centre |
| May 19 | DET | | 4 | 11 |  | STL | May 19 07:45 PM EDT (Mon) | Busch Stadium |
| May 20 | DET | | 5 | 4 | | STL | May 20 07:45 PM EDT (Tue) | Busch Stadium |
| May 21 | DET | | 5 | 1 | | STL | May 21 01:15 PM EDT (Wed) | Busch Stadium |
| May 22 | CLE |  | 7 | 0 | | DET | May 22 06:40 PM EDT (Thu) | Comerica Park |
| May 23 | CLE | | 3 | 1 | | DET | May 23 07:10 PM EDT (Fri) | Comerica Park |
| May 24 | CLE | | 7 | 5 | | DET | May 24 07:15 PM EDT (Sat) | Comerica Park |
| May 25 | CLE | | 0 | 5 | | DET | May 25 11:35 AM EDT (Sun) | Comerica Park |
| May 26 | SF |  | 1 | 3 | | DET | May 26 01:10 PM EDT (Mon) | Comerica Park |
| May 27 | SF | | 1 | 3 | | DET | May 27 06:40 PM EDT (Tue) | Comerica Park |
| May 28 | SF | | 3 | 4 | | DET | May 28 01:10 PM EDT (Wed) | Comerica Park |
| May 30 | DET | | 7 | 5 |  | KC | May 30 08:10 PM EDT (Fri) | Kauffman Stadium |
| May 31 | DET | | 0 | 1 | | KC | May 31 04:10 PM EDT (Sat) | Kauffman Stadium |
