| Date | Away | | | | | Home | First Pitch | Where |
|---|
| Mar 27 | MIL |  | 2 | 4 |  | NYY | Mar 27 03:05 PM EDT (Thu) | Yankee Stadium |
| Mar 29 | MIL | | 9 | 20 | | NYY | Mar 29 01:05 PM EDT (Sat) | Yankee Stadium |
| Mar 30 | MIL | | 3 | 12 | | NYY | Mar 30 01:35 PM EDT (Sun) | Yankee Stadium |
| Apr 01 | ARI |  | 7 | 5 | | NYY | Apr 01 07:05 PM EDT (Tue) | Yankee Stadium |
| Apr 02 | ARI | | 4 | 3 | | NYY | Apr 02 07:05 PM EDT (Wed) | Yankee Stadium |
| Apr 03 | ARI | | 7 | 9 | | NYY | Apr 03 07:05 PM EDT (Thu) | Yankee Stadium |
| Apr 04 | NYY | | 9 | 4 |  | PIT | Apr 04 04:12 PM EDT (Fri) | PNC Park |
| Apr 05 | NYY | | 10 | 4 | | PIT | Apr 05 04:05 PM EDT (Sat) | PNC Park |
| Apr 06 | NYY | | 4 | 5 | | PIT | Apr 06 01:35 PM EDT (Sun) | PNC Park |
| Apr 07 | NYY | | 2 | 6 |  | DET | Apr 07 03:10 PM EDT (Mon) | Comerica Park |
| Apr 08 | NYY | | 0 | 5 | | DET | Apr 08 01:10 PM EDT (Tue) | Comerica Park |
| Apr 09 | NYY | | 4 | 3 | | DET | Apr 09 01:10 PM EDT (Wed) | Comerica Park |
| Apr 11 | SF |  | 9 | 1 | | NYY | Apr 11 07:05 PM EDT (Fri) | Yankee Stadium |
| Apr 12 | SF | | 4 | 8 | | NYY | Apr 12 03:05 PM EDT (Sat) | Yankee Stadium |
| Apr 13 | SF | | 5 | 4 | | NYY | Apr 13 01:35 PM EDT (Sun) | Yankee Stadium |
| Apr 14 | KC |  | 1 | 4 | | NYY | Apr 14 07:05 PM EDT (Mon) | Yankee Stadium |
| Apr 15 | KC | | 2 | 4 | | NYY | Apr 15 07:05 PM EDT (Tue) | Yankee Stadium |
| Apr 16 | KC | | 3 | 4 | | NYY | Apr 16 07:05 PM EDT (Wed) | Yankee Stadium |
| Apr 17 | NYY | | 6 | 3 |  | TB | Apr 17 07:05 PM EDT (Thu) | George M. Steinbrenner Field |
| Apr 18 | NYY | | 1 | 0 | | TB | Apr 18 07:05 PM EDT (Fri) | George M. Steinbrenner Field |
| Apr 19 | NYY | | 8 | 10 | | TB | Apr 19 04:10 PM EDT (Sat) | George M. Steinbrenner Field |
| Apr 20 | NYY | | 4 | 0 | | TB | Apr 20 01:40 PM EDT (Sun) | George M. Steinbrenner Field |
| Apr 21 | NYY | | 4 | 6 |  | CLE | Apr 21 06:10 PM EDT (Mon) | Progressive Field |
| Apr 22 | NYY | | 2 | 3 | | CLE | Apr 22 06:10 PM EDT (Tue) | Progressive Field |
| Apr 23 | NYY | | 5 | 1 | | CLE | Apr 23 01:10 PM EDT (Wed) | Progressive Field |
| Apr 25 | TOR |  | 4 | 2 | | NYY | Apr 25 07:05 PM EDT (Fri) | Yankee Stadium |
| Apr 26 | TOR | | (postponed) | | NYY | Apr 26 01:40 PM EDT (Sat) | Yankee Stadium (resch Apr 27) |
| Apr 27 | TOR | | 2 | 11 | | NYY | Apr 27 01:35 PM EDT (Sun) | Yankee Stadium |
| Apr 27 | TOR | | 1 | 5 | | NYY | Apr 27 01:40 PM EDT (Sun) | Yankee Stadium |
| Apr 28 | NYY | | 3 | 4 |  | BAL | Apr 28 06:35 PM EDT (Mon) | Oriole Park at Camden Yards |
| Apr 29 | NYY | | 15 | 3 | | BAL | Apr 29 06:35 PM EDT (Tue) | Oriole Park at Camden Yards |
| Apr 30 | NYY | | 4 | 5 | | BAL | Apr 30 06:35 PM EDT (Wed) | Oriole Park at Camden Yards |
| May 02 | TB | | 0 | 3 | | NYY | May 02 07:05 PM EDT (Fri) | Yankee Stadium |
| May 03 | TB | | 3 | 2 | | NYY | May 03 01:05 PM EDT (Sat) | Yankee Stadium |
| May 04 | TB | | 7 | 5 | | NYY | May 04 01:35 PM EDT (Sun) | Yankee Stadium |
| May 05 | SD |  | 4 | 3 | | NYY | May 05 07:05 PM EDT (Mon) | Yankee Stadium |
| May 06 | SD | | 3 | 12 | | NYY | May 06 07:05 PM EDT (Tue) | Yankee Stadium |
| May 07 | SD | | 3 | 4 | | NYY | May 07 07:05 PM EDT (Wed) | Yankee Stadium |
| May 09 | NYY | | 10 | 2 |  | LV | May 09 10:05 PM EDT (Fri) | Sutter Health Park |
| May 10 | NYY | | 7 | 11 | | LV | May 10 04:05 PM EDT (Sat) | Sutter Health Park |
| May 11 | NYY | | 12 | 2 | | LV | May 11 04:05 PM EDT (Sun) | Sutter Health Park |
| May 12 | NYY | | 11 | 5 |  | SEA | May 12 09:40 PM EDT (Mon) | T-Mobile Park |
| May 13 | NYY | | 1 | 2 | | SEA | May 13 09:40 PM EDT (Tue) | T-Mobile Park |
| May 14 | NYY | | 3 | 2 | | SEA | May 14 04:10 PM EDT (Wed) | T-Mobile Park |
| May 16 | NYM |  | 2 | 6 | | NYY | May 16 07:05 PM EDT (Fri) | Yankee Stadium |
| May 17 | NYM | | 3 | 2 | | NYY | May 17 01:05 PM EDT (Sat) | Yankee Stadium |
| May 18 | NYM | | 2 | 8 | | NYY | May 18 07:10 PM EDT (Sun) | Yankee Stadium |
| May 20 | TEX |  | 2 | 5 | | NYY | May 20 07:05 PM EDT (Tue) | Yankee Stadium |
| May 21 | TEX | | 3 | 4 | | NYY | May 21 07:05 PM EDT (Wed) | Yankee Stadium |
| May 22 | TEX | | 0 | 1 | | NYY | May 22 12:35 PM EDT (Thu) | Yankee Stadium |
| May 23 | NYY | | 2 | 3 |  | COL | May 23 08:40 PM EDT (Fri) | Coors Field |
| May 24 | NYY | | 13 | 1 | | COL | May 24 04:10 PM EDT (Sat) | Coors Field |
| May 25 | NYY | | 5 | 4 | | COL | May 25 03:10 PM EDT (Sun) | Coors Field |
| May 26 | NYY | | 5 | 1 |  | LAA | May 26 09:38 PM EDT (Mon) | Angel Stadium |
| May 27 | NYY | | 3 | 2 | | LAA | May 27 09:38 PM EDT (Tue) | Angel Stadium |
| May 28 | NYY | | 1 | 0 | | LAA | May 28 09:38 PM EDT (Wed) | Angel Stadium |
| May 30 | NYY | | 5 | 8 |  | LAD | May 30 10:10 PM EDT (Fri) | Dodger Stadium |
| May 31 | NYY | | 2 | 18 | | LAD | May 31 07:15 PM EDT (Sat) | Dodger Stadium |
| Jun 01 | NYY | | 7 | 3 | | LAD | Jun 01 07:10 PM EDT (Sun) | Dodger Stadium |
| Jun 03 | CLE | | 2 | 3 | | NYY | Jun 03 07:05 PM EDT (Tue) | Yankee Stadium |
| Jun 04 | CLE | | 4 | 0 | | NYY | Jun 04 07:05 PM EDT (Wed) | Yankee Stadium |
| Jun 05 | CLE | | 0 | 4 | | NYY | Jun 05 07:05 PM EDT (Thu) | Yankee Stadium |
| Jun 06 | BOS |  | 6 | 9 | | NYY | Jun 06 07:05 PM EDT (Fri) | Yankee Stadium |
| Jun 07 | BOS | | 10 | 7 | | NYY | Jun 07 07:35 PM EDT (Sat) | Yankee Stadium |
| Jun 08 | BOS | | 11 | 7 | | NYY | Jun 08 07:10 PM EDT (Sun) | Yankee Stadium |
| Jun 10 | NYY | | 10 | 2 | | KC | Jun 10 07:40 PM EDT (Tue) | Kauffman Stadium |
| Jun 11 | NYY | | 6 | 3 | | KC | Jun 11 07:40 PM EDT (Wed) | Kauffman Stadium |
| Jun 12 | NYY | | 1 | 0 | | KC | Jun 12 07:40 PM EDT (Thu) | Kauffman Stadium |
| Jun 13 | NYY | | 1 | 2 | | BOS | Jun 13 07:10 PM EDT (Fri) | Fenway Park |
| Jun 14 | NYY | | 3 | 4 | | BOS | Jun 14 07:15 PM EDT (Sat) | Fenway Park |
| Jun 15 | NYY | | 0 | 2 | | BOS | Jun 15 01:35 PM EDT (Sun) | Fenway Park |
| Jun 16 | LAA | | 1 | 0 | | NYY | Jun 16 07:05 PM EDT (Mon) | Yankee Stadium |
| Jun 17 | LAA | | 4 | 0 | | NYY | Jun 17 07:05 PM EDT (Tue) | Yankee Stadium |
| Jun 18 | LAA | | 3 | 2 | | NYY | Jun 18 07:05 PM EDT (Wed) | Yankee Stadium |
| Jun 19 | LAA | | 3 | 7 | | NYY | Jun 19 01:05 PM EDT (Thu) | Yankee Stadium |
| Jun 20 | BAL | | 5 | 3 | | NYY | Jun 20 07:05 PM EDT (Fri) | Yankee Stadium |
| Jun 21 | BAL | | 0 | 9 | | NYY | Jun 21 01:05 PM EDT (Sat) | Yankee Stadium |
| Jun 22 | BAL | | 2 | 4 | | NYY | Jun 22 11:35 AM EDT (Sun) | Yankee Stadium |
| Jun 23 | NYY | | 1 | 6 |  | CIN | Jun 23 07:10 PM EDT (Mon) | Great American Ball Park |
| Jun 24 | NYY | | 4 | 5 | | CIN | Jun 24 07:10 PM EDT (Tue) | Great American Ball Park |
| Jun 25 | NYY | | 7 | 1 | | CIN | Jun 25 07:10 PM EDT (Wed) | Great American Ball Park |
| Jun 27 | LV | | 0 | 3 | | NYY | Jun 27 07:05 PM EDT (Fri) | Yankee Stadium |
| Jun 28 | LV | | 7 | 0 | | NYY | Jun 28 01:05 PM EDT (Sat) | Yankee Stadium |
| Jun 29 | LV | | 5 | 12 | | NYY | Jun 29 01:35 PM EDT (Sun) | Yankee Stadium |
| Jun 30 | NYY | | 4 | 5 | | TOR | Jun 30 07:07 PM EDT (Mon) | Rogers Centre |
